Factors Affecting Potentially Inappropriate Medications (PIMs) Based on STOPP/START Criteria in Geriatric Patients at RSUD Dr. Soedomo Trenggalek

Widyaningrum, Esti Ambar and Nur Satya Irawati, Reny and Kurniawati, Evi and Fitriani, Marina and Fajriyah, Shofiatul and Lestari, Tri Puji (2024) Factors Affecting Potentially Inappropriate Medications (PIMs) Based on STOPP/START Criteria in Geriatric Patients at RSUD Dr. Soedomo Trenggalek. Jurnal Farmasi Galenika (Galenika Journal of Pharmacy), 10 (2). pp. 171-182. ISSN 2442-8744 (electronic); 2442-7284 (printed)

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Abstract

Background: Geriatric patients often have multiple comorbidities and decreased physiological function, leading to polypharmacy and potential exposure to inappropriate medications (PIMs). Objectives: This study investigates geriatric inpatients' characteristic profiles, evaluates PIMs using STOPP/START criteria, and explores factors influencing PIM incidence. Method: This study employed a retrospective observational analytical approach. The sampling technique was purposive sampling. The sample involved in this study was 312 patients. Results: The geriatric patients involved in this study had the following characteristics: 62% male and 38% female; 69% youngest-old (65-74 years), 30% middle-old (75-90 years), and 1% oldest-old (>90 years); 87% with BPJS service type and 13% with general service type; main diagnosis groups of the patients were gastrointestinal of 9%, cardiovascular of 31%, respiratory of 3%, neurological of 1%, infection of 11%, endocrine of 13%, genitourinary of 15%, immune an malignant of 1%, blood of 11%, musculoskeletal of 2%, eyes of 2% and skin of 1%; 13% patients had one disease, 43% had two diseases, 25% had three diseases, and 19% had ≥ four diseases;29% had 15 drugs, 50% had 6-10 drugs, 17% had 11-15 drugs, 3% had 20 drugs, and 1% had ≥ 20 drugs. There were 72 PIMs based on STOPP/START criteria. The results of the analysis using the C contingency coefficient test showed the following factors, such as gender (p-value of 0.894), age (p-value of 0.470), type of service (p-value of 0.166), main diagnosis (p-value of 0.042), number of illness (p-value of 0.106), and number of drugs (p-value of 0.182). Conclusion: There is a correlation between the main diagnosis factor and PIMs with a p-value of 0.042 (p-value < 0.05).

Item Type: Article
Kata Kunci: GeriatricElderlyPIMsSTOPP/START
Subjects: R Medicine > RM Therapeutics. Pharmacology
R Medicine > RS Pharmacy and materia medica
Divisions: Karya Dosen > Farmasi
Depositing User: admin
Date Deposited: 07 Mar 2025 03:17
Last Modified: 07 Mar 2025 03:17
URI: http://eprints.iik.ac.id/id/eprint/462

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